I've just tried a very quick test(s) on WCML-N with the Handover scenario--turning V-Sync off gives a frame rate of 28-31 (as reported by the in game counter), rising slightly to 36 at the Bridge Street marker, a big drop to 15 at the start of Polmadie---a very brief one though, almost immediately back up to 26, rising to 34 at the end of the depot.
The same run but using the "Maximum Power" option as recommended by Peter (I usually use the default of "Optimal Power") gave the same figures--give or take a couple of points either way.
Dropping back to my usual configuration thankfully got rid of the screen tearing when panning the view in the cab
Maybe more by luck than judgement I've found the optimal in game settings for the graphics to suit my hardware, now on a 970, but other than being able to run happily with 3x3 SSAA they're no different to what I used with a 960 (2x2 SSAA) nor with the settings used with a 550 (2x1 or 1x2 SSAA---I could never decide which worked/looked best)
In addition to the PC specs Pete, could you post what your in gane graphics settings are?