Yes, E10 needs TS2015. But the route (and the 189 and 628) runs even under TS2014. Of course without the new weather system, but it runs fine. But the route looks way better with the new weather system activated and its new environment lighting.
And just for info: the track layout and signalling was built back in TS2012 (what not means that it isn't good ... the possibilities were there, even in TS2012, e.g. full correct SE, eased gradient changes (manually built with short track sections)). The route got the newest H/V signal scripts (for more realistic scenario possibilities), but it was built with a beta/first version of the signal system as it wans't released to the public audience in 2012. There are balieses in there for a possible GPS (for EBuLa systems) and FIS (passenger announcements) systems what tells with triggers where you are and what station comes next (but unfortunately both are not used until today). The tracks and catenary are high quality stuff. Tracks have normal maps on each layer (bed, top sleeper, rails and the attachment stuff) for better look and feel (yes, they are very dark colored, but that was intended because of the flickering with brighter colored tracks, what i won't to see). Catenary is a very own story. Built from hundred of single components, placed full manually over 9 months, this is something you didn't see on any route yet, and you will not see on future routes (except the new RLB SWB and possible new routes from Aerosoft) i guess, naa, i know. To many work to do with only a visible profit (not money, as there is no one who will pay for that extreme heavy work). And if someone think he can use this stuff on a freeware route, no. First because i won't it, second who tries will see why
Even if it is the default BR52